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Structural and functional insights into the B30.2/SPRY domain

The B30.2/SPRY domain is present in ∼700 eukaryotic (∼150 human) proteins, including medically important proteins such as TRIM5α and Pyrin. Nonetheless, the functional role of this modular domain remained unclear. Here, we report the crystal structure of an SPRY-SOCS box family protein GUSTAVUS in c...

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Detalhes bibliográficos
Main Authors: Woo, Jae-Sung, Imm, Joon-Hyuk, Min, Chang-Ki, Kim, Kyung-Jin, Cha, Sun-Shin, Oh, Byung-Ha
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422157/
https://ncbi.nlm.nih.gov/pubmed/16498413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600994
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