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DNA interstrand crosslink repair during G1 involves nucleotide excision repair and DNA polymerase ζ

The repair mechanisms acting on DNA interstrand crosslinks (ICLs) in eukaryotes are poorly understood. Here, we provide evidence for a pathway of ICL processing that uses components from both nucleotide excision repair (NER) and translesion synthesis (TLS) and predominates during the G1 phase of the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sarkar, Sovan, Davies, Adelina A, Ulrich, Helle D, McHugh, Peter J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422152/
https://ncbi.nlm.nih.gov/pubmed/16482220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600993
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