Protection Against Fas-Mediated and Tumor Necrosis Factor Receptor 1-Mediated Liver Injury by Blockade of FADD Without Loss of Nuclear Factor-κB Activation

OBJECTIVE: To investigate the role of FADD (Fas-associated protein with death domain) in Fas and tumor necrosis factor receptor 1 (TNFR1)-mediated hepatic injury and inflammatory response in vivo. SUMMARY BACKGROUND DATA: Fas and TNFR1 are cell surface molecules that trigger apoptosis or inflammatio...

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Detalhes bibliográficos
Principais autores: Seino, Ken-ichiro, Setoguchi, Yasuhiro, Ogino, Takashi, Kayagaki, Nobuhiko, Akiba, Hisaya, Nakano, Hiroyasu, Taniguchi, Hideki, Takada, Yasutsugu, Yuzawa, Kenji, Todoroki, Takeshi, Fukuchi, Yoshinosuke, Yagita, Hideo, Okumura, Ko, Fukao, Katashi
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422094/
https://ncbi.nlm.nih.gov/pubmed/11685033
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