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Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
BACKGROUND: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selection methods are limited by uncertainties in RNA secondary structure prediction. If all the predicted structures of a giv...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1421440/ https://ncbi.nlm.nih.gov/pubmed/16526963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-122 |
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