Interleukin 12 Secretion Enhances Antitumor Efficacy of Oncolytic Herpes Simplex Viral Therapy for Colorectal Cancer

OBJECTIVE: To assess the strategy of combining oncolytic herpes simplex virus (HSV) therapy with immunomodulatory therapy as treatment for experimental colon cancer. The oncolytic HSV recombinant NV1023 and the interleukin 12 (IL-12)-secreting oncolytic NV1042 virus were evaluated in vitro and in vi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bennett, Joseph J., Malhotra, Sandeep, Wong, Richard J., Delman, Keith, Zager, Jonathan, St-Louis, Maryse, Johnson, Paul, Fong, Yuman
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2001
Pynciau:
Scientific Papers of the Southern Surgical Association
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421325/
https://ncbi.nlm.nih.gov/pubmed/11371740
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