Antibody-Independent, Interleukin-17A-Mediated, Cross-Serotype Immunity to Pneumococci in Mice Immunized Intranasally with the Cell Wall Polysaccharide

Serotype-specific immunity to Streptococcus pneumoniae is conferred by antibodies to the capsular polysaccharides, which define the 90 known serotypes. Whether antibody to the species-common cell wall polysaccharide (C-Ps) is protective has been a matter of controversy. Here we show that C-Ps given...

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Main Authors: Malley, Richard, Srivastava, Amit, Lipsitch, Marc, Thompson, Claudette M., Watkins, Claire, Tzianabos, Arthur, Anderson, Porter W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418935/
https://ncbi.nlm.nih.gov/pubmed/16552049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.4.2187-2195.2006
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