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Antigen-Responsive CD4(+) T Cells from C3H Mice Chronically Infected with Leishmania amazonensis Are Impaired in the Transition to an Effector Phenotype

C3HeB/FeJ mice challenged with Leishmania major develop a polarized Th1 response and subsequently heal, whereas Leishmania amazonensis challenge leads to chronic lesions with high parasite loads at 10 weeks postinfection. In this study, a comparison of draining lymph node cells from L. amazonensis-...

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Detalhes bibliográficos
Main Authors: Ramer, Amanda E., Vanloubbeeck, Yannick F., Jones, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418674/
https://ncbi.nlm.nih.gov/pubmed/16495525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.3.1547-1554.2006
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