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Perforin and Gamma Interferon Are Critical CD8(+) T-Cell-Mediated Responses in Vaccine-Induced Immunity against Leishmania amazonensis Infection

Previous studies have demonstrated that protection against New World leishmaniasis caused by Leishmania amazonensis can be elicited by immunization with the developmentally regulated Leishmania amastigote antigen, P-8. In this study, several independent experimental approaches were employed to inves...

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Detalhes bibliográficos
Main Authors: Colmenares, María, Kima, Peter E., Samoff, Erika, Soong, Lynn, McMahon-Pratt, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155724/
https://ncbi.nlm.nih.gov/pubmed/12761096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3172-3182.2003
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