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Senescence of Human Fibroblasts after Psoralen Photoactivation Is Mediated by ATR Kinase and Persistent DNA Damage Foci at Telomeres

Cellular senescence is a phenotype that is likely linked with aging. Recent concepts view different forms of senescence as permanently maintained DNA damage responses partially characterized by the presence of senescence-associated DNA damage foci at dysfunctional telomeres. Irradiation of primary h...

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Autors principals: Hovest, Miriam Grosse, Brüggenolte, Nicole, Hosseini, Kijawasch Shah, Krieg, Thomas, Herrmann, Gernot
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1415309/
https://ncbi.nlm.nih.gov/pubmed/16436511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-08-0701
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