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Heme Is a Carbon Monoxide Receptor for Large-Conductance Ca(2+)-Activated K(+) Channels

Carbon monoxide (CO) is an endogenous paracrine and autocrine gaseous messenger that regulates physiological functions in a wide variety of tissues. CO induces vasodilation by activating arterial smooth muscle large–conductance Ca(2+)-activated potassium (BK(Ca)) channels. However, the mechanism by...

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Hlavní autoři: Jaggar, Jonathan H., Li, Anlong, Parfenova, Helena, Liu, Jianxi, Umstot, Edward S., Dopico, Alejandro M., Leffler, Charles W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1415201/
https://ncbi.nlm.nih.gov/pubmed/16166559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000186180.47148.7b
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