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Carbon monoxide as an endogenous vascular modulator

Carbon monoxide (CO) is produced by heme oxygenase (HO)-catalyzed heme degradation to CO, iron, and biliverdin. HO has two active isoforms, HO-1 (inducible) and HO-2 (constitutive). HO-2, but not HO-1, is highly expressed in endothelial and smooth muscle cells and in adjacent astrocytes in the brain...

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Autori principali: Leffler, Charles W., Parfenova, Helena, Jaggar, Jonathan H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129910/
https://ncbi.nlm.nih.gov/pubmed/21498777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00230.2011
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