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Bottleneck-mediated quasispecies restriction during spread of an RNA virus from inoculation site to brain

The amplification of RNA viruses such as poliovirus is associated with high error rates, and the resulting diversity likely facilitates viral survival within an infected host. However, within individual tissues of infected hosts, there may be barriers to viral spread that limit genome sampling. We t...

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Bibliografiset tiedot
Päätekijät: Pfeiffer, Julie K., Kirkegaard, Karla
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1414638/
https://ncbi.nlm.nih.gov/pubmed/16567621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600834103
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