A carregar...
A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity
Ribavirin is a nucleotide analog that can be incorporated by viral polymerases, causing mutations by allowing base mismatches. It is currently used therapeutically as an antiviral drug during hepatitis C virus infections. During the amplification of poliovirus genomic RNA or hepatitis C replicons, e...
Na minha lista:
| Main Authors: | , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165868/ https://ncbi.nlm.nih.gov/pubmed/12754380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232294100 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|