Kinetics and Thermodynamics of Type VIII β-Turn Formation: A CD, NMR, and Microsecond Explicit Molecular Dynamics Study of the GDNP Tetrapeptide

We report an experimental and theoretical study on type VIII β-turn using a designed peptide of sequence GDNP. CD and NMR studies reveal that this peptide exists in equilibrium between type VIII β-turn and extended conformations. Extensive MD simulations give a description of the free energy landsca...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fuchs, Patrick F. J., Bonvin, Alexandre M. J. J., Bochicchio, Brigida, Pepe, Antonietta, Alix, Alain J. P., Tamburro, Antonio M.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Biophysical Theory and Modeling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1414573/
https://ncbi.nlm.nih.gov/pubmed/16443656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.074401
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados