53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis

p53-binding protein 1 (53BP1) participates in the cellular response to DNA double-stranded breaks where it associates with various DNA repair/cell cycle factors including the H2AX histone variant. Mice deficient for 53BP1 (53BP1(−/−)) are sensitive to ionizing radiation and immunodeficient because o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Morales, Julio C., Franco, Sonia, Murphy, Michael M., Bassing, Craig H., Mills, Kevin D., Adams, Melissa M., Walsh, Nicole C., Manis, John P., Rassidakis, George Z., Alt, Frederick W., Carpenter, Phillip B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413919/
https://ncbi.nlm.nih.gov/pubmed/16492765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511259103
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados