RabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cells

We recently reported that RabGEF1 is a negative regulator of high-affinity Fc receptor for IgE (FcεRI)-dependent mast cell activation and that mice lacking RabGEF1 develop severe skin inflammation and increased numbers of dermal mast cells. To better understand how RabGEF1 can regulate signaling eve...

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Detalhes bibliográficos
Main Authors: Kalesnikoff, Janet, Rios, Eon J., Chen, Ching-Cheng, Nakae, Susumu, Zabel, Brian A., Butcher, Eugene C., Tsai, Mindy, Tam, See-Ying, Galli, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413845/
https://ncbi.nlm.nih.gov/pubmed/16533754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511191103
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