RabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cells

We recently reported that RabGEF1 is a negative regulator of high-affinity Fc receptor for IgE (FcεRI)-dependent mast cell activation and that mice lacking RabGEF1 develop severe skin inflammation and increased numbers of dermal mast cells. To better understand how RabGEF1 can regulate signaling eve...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kalesnikoff, Janet, Rios, Eon J., Chen, Ching-Cheng, Nakae, Susumu, Zabel, Brian A., Butcher, Eugene C., Tsai, Mindy, Tam, See-Ying, Galli, Stephen J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2006
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413845/
https://ncbi.nlm.nih.gov/pubmed/16533754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511191103
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