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κ opioids selectively control dopaminergic neurons projecting to the prefrontal cortex

Dopaminergic afferents arising from the ventral tegmental area (VTA) are crucial elements in the neural circuits that mediate arousal, motivation, and reinforcement. Two major targets of these afferents are the medial prefrontal cortex (mPFC) and the nucleus accumbens (NAc). Whereas dopamine (DA) in...

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Autors principals: Margolis, Elyssa B., Lock, Hagar, Chefer, Vladimir I., Shippenberg, Toni S., Hjelmstad, Gregory O., Fields, Howard L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413839/
https://ncbi.nlm.nih.gov/pubmed/16477003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511159103
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