Association of brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2) with recycling endosomes during transferrin uptake

ADP-ribosylation factors (ARFs) are critical in vesicular trafficking. Brefeldin A-inhibited guanine nucleotide-exchange protein (BIG)1 and BIG2 activate ARFs by accelerating replacement of bound GDP with GTP. Additional and differing functions of these ≈200-kDa proteins are now being recognized, as...

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Hlavní autoři: Shen, Xiaoyan, Xu, Kai-Feng, Fan, Qingyuan, Pacheco-Rodriguez, Gustavo, Moss, Joel, Vaughan, Martha
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413799/
https://ncbi.nlm.nih.gov/pubmed/16477018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510599103
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