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BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein, is required for correct glycosylation and function of integrin β1

Glycosylation of β1 integrin (β1) in the Golgi complex has been related to its function in multiple cell processes, e.g., invasiveness, matrix adhesion, and migration. Brefeldin A-inhibited guanine nucleotide-exchange proteins (BIG) 1 and BIG2 activate human ADP-ribosylation factors (ARF) 1 and ARF3...

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Detalhes bibliográficos
Main Authors: Shen, Xiaoyan, Hong, Myoung-Soon, Moss, Joel, Vaughan, Martha
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783117/
https://ncbi.nlm.nih.gov/pubmed/17227842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610535104
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