Human Cytomegalovirus Infection Leads to Accumulation of Geminin and Inhibition of the Licensing of Cellular DNA Replication

Previous studies have shown that infection of G(0)-synchronized human fibroblasts by human cytomegalovirus (HCMV) results in a block to cellular DNA synthesis. In this study, we have examined the effect of viral infection on the formation of the host cell DNA prereplication complex (pre-RC). We foun...

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Hlavní autoři: Biswas, Nilima, Sanchez, Veronica, Spector, Deborah H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC141111/
https://ncbi.nlm.nih.gov/pubmed/12551974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2369-2376.2003
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