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Human Cytomegalovirus Infection Leads to Accumulation of Geminin and Inhibition of the Licensing of Cellular DNA Replication

Previous studies have shown that infection of G(0)-synchronized human fibroblasts by human cytomegalovirus (HCMV) results in a block to cellular DNA synthesis. In this study, we have examined the effect of viral infection on the formation of the host cell DNA prereplication complex (pre-RC). We foun...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Biswas, Nilima, Sanchez, Veronica, Spector, Deborah H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141111/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12551974/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.4.2369-2376.2003
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