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Regulation of CDC6, Geminin, and CDT1 in Human Cells that Undergo Polyploidization

Endomitosis is the process by which mammalian megakaryocytes become polyploid during terminal differentiation. As in other endoreplicating cells, cyclin-cdk complexes are distinctly regulated, probably to overcome the strict mechanisms that prevent rereplication in most somatic cells. We have asked...

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Detalhes bibliográficos
Main Authors: Bermejo, Rodrigo, Vilaboa, Nuria, Calés, Carmela
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133609/
https://ncbi.nlm.nih.gov/pubmed/12429841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-04-0217
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