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Regulation of CDC6, Geminin, and CDT1 in Human Cells that Undergo Polyploidization

Endomitosis is the process by which mammalian megakaryocytes become polyploid during terminal differentiation. As in other endoreplicating cells, cyclin-cdk complexes are distinctly regulated, probably to overcome the strict mechanisms that prevent rereplication in most somatic cells. We have asked...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Bermejo, Rodrigo, Vilaboa, Nuria, Calés, Carmela
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Cell Biology 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133609/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12429841/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-04-0217
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