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PrP Polymorphisms Tightly Control Sheep Prion Replication in Cultured Cells

Prion diseases are fatal neurodegenerative disorders of animals and humans that are characterized by the conversion of the host-encoded prion protein (PrP) to an abnormal isoform. In several species, including humans, polymorphisms in the gene encoding the PrP protein tightly control susceptibility...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Sabuncu, Elifsu, Petit, Stéphanie, Le Dur, Annick, Lan Lai, Thanh, Vilotte, Jean-Luc, Laude, Hubert, Vilette, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141085/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12552009/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.4.2696-2700.2003
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