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Rod and cone visual cycle consequences of a null mutation in the 11-cis-retinol dehydrogenase gene in man

Vertebrate vision starts with photoisomerization of the 11-cis-retinal chromophore to all-trans-retinal. Biosynthesis of 11-cis-retinal is required to maintain vision. A key enzyme catalyzing the oxidation of 11-cis-retinol is 11-cis-retinol dehydrogenase (11-cis-RDH), which is encoded by the RDH5 g...

詳細記述

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書誌詳細
主要な著者: CIDECIYAN, ARTUR V., HAESELEER, FRANÇOISE, FARISS, ROBERT N., ALEMAN, TOMAS S., JANG, GEENG-FU, VERLINDE, CHRISTOPHE L. M. J., MARMOR, MICHAEL F., JACOBSON, SAMUEL G., PALCZEWSKI, KRZYSZTOF
フォーマット: Artigo
言語:Inglês
出版事項: 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410813/
https://ncbi.nlm.nih.gov/pubmed/11153648
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