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Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells

INTRODUCTION: The metastatic progression of cancer is a direct result of the disregulation of numerous cellular signaling pathways, including those associated with adhesion, migration, and invasion. Members of the Rac family of small GTPases are known to act as regulators of actin cytoskeletal struc...

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Bibliografiska uppgifter
Huvudupphovsmän: Baugher, Paige J, Krishnamoorthy, Lakshmi, Price, Janet E, Dharmawardhane, Surangani F
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2005
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410764/
https://ncbi.nlm.nih.gov/pubmed/16280046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1329
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