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Specificity of activation by phosphoinositides determines lipid regulation of Kir channels

Phosphoinositides are critical regulators of ion channel and transporter activity. Defects in interactions of inwardly rectifying potassium (Kir) channels with phosphoinositides lead to disease. ATP-sensitive K(+) channels (K(ATP)) are unique among Kir channels in that they serve as metabolic sensor...

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Bibliografiske detaljer
Main Authors: Rohács, Tibor, Lopes, Coeli M. B., Jin, Taihao, Ramdya, Pavan P., Molnár, Zoltán, Logothetis, Diomedes E.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC141067/
https://ncbi.nlm.nih.gov/pubmed/12525701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0236364100
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