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PIP(2) hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K(+) channels

Two-pore (2-P) domain potassium channels are implicated in the control of the resting membrane potential, hormonal secretion, and the amplitude, frequency and duration of the action potential. These channels are strongly regulated by hormones and neurotransmitters. Little is known, however, about th...

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Detalhes bibliográficos
Main Authors: Lopes, Coeli M B, Rohács, Tibor, Czirják, Gábor, Balla, Tamás, Enyedi, Péter, Logothetis, Diomedes E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456043/
https://ncbi.nlm.nih.gov/pubmed/15677683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.081935
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