Chaperones increase association of tau protein with microtubules

Molecular chaperones and their functions in protein folding have been implicated in several neurodegenerative diseases, including Parkinson's disease and Huntington's disease, which are characterized by accumulation of protein aggregates (e.g., α-synuclein and huntingtin, respectively). Th...

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Bibliografiska uppgifter
Huvudupphovsmän: Dou, Fei, Netzer, William J., Tanemura, Kentaro, Li, Feng, Hartl, F. Ulrich, Takashima, Akihiko, Gouras, Gunnar K., Greengard, Paul, Xu, Huaxi
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2003
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC141063/
https://ncbi.nlm.nih.gov/pubmed/12522269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242720499
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