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Global genome repair is required to activate KIN17, a UVC-responsive gene involved in DNA replication
UV light provokes DNA lesions that interfere with replication and transcription. These lesions may compromise cell viability and usually are removed by nucleotide excision repair (NER). In humans, inactivation of NER is associated with three rare autosomal recessive inherited disorders: xeroderma pi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC141045/ https://ncbi.nlm.nih.gov/pubmed/12525703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0236176100 |
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