Global genome repair is required to activate KIN17, a UVC-responsive gene involved in DNA replication

UV light provokes DNA lesions that interfere with replication and transcription. These lesions may compromise cell viability and usually are removed by nucleotide excision repair (NER). In humans, inactivation of NER is associated with three rare autosomal recessive inherited disorders: xeroderma pi...

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Bibliographic Details
Main Authors: Masson, Christel, Menaa, Farid, Pinon-Lataillade, Ghislaine, Frobert, Yveline, Chevillard, Sylvie, Radicella, J. Pablo, Sarasin, Alain, Angulo, Jaime F.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC141045/
https://ncbi.nlm.nih.gov/pubmed/12525703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0236176100
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