Global genome repair is required to activate KIN17, a UVC-responsive gene involved in DNA replication

UV light provokes DNA lesions that interfere with replication and transcription. These lesions may compromise cell viability and usually are removed by nucleotide excision repair (NER). In humans, inactivation of NER is associated with three rare autosomal recessive inherited disorders: xeroderma pi...

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Bibliografiske detaljer
Main Authors: Masson, Christel, Menaa, Farid, Pinon-Lataillade, Ghislaine, Frobert, Yveline, Chevillard, Sylvie, Radicella, J. Pablo, Sarasin, Alain, Angulo, Jaime F.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC141045/
https://ncbi.nlm.nih.gov/pubmed/12525703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0236176100
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