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Impaired B cell development and function in mice with a targeted disruption of the homeobox gene Hex
Hex is a homeobox gene that is expressed in all stages of B cell development except plasma cells. We studied lymphocyte development in the absence of Hex by using the RAG1-deficient blastocyst complementation system because homozygous disruption of Hex is embryonic lethal. Hex(−/−);RAG1(−/−) chimeri...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC141034/ https://ncbi.nlm.nih.gov/pubmed/12522149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0236979100 |
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