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Evidence that exposure of the telomere 3′ overhang sequence induces senescence

Normal human cells cease proliferation after a finite number of population doublings, a phenomenon termed replicative senescence. This process, first convincingly described by Hayflick and Moorhead [Hayflick, L. & Moorhead, P. S. (1961) Exp. Cell Res. 25, 595–621] for cultured human fibroblasts...

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Bibliografski detalji
Glavni autori: Li, Guang-Zhi, Eller, Mark S., Firoozabadi, Reza, Gilchrest, Barbara A.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC141029/
https://ncbi.nlm.nih.gov/pubmed/12515865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0235444100
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