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Routes to S-nitroso-hemoglobin formation with heme redox and preferential reactivity in the β subunits

Previous studies of the interactions of NO with human hemoglobin have implied the predominance of reaction channels that alternatively eliminate NO by converting it to nitrate, or tightly complex it on the α subunit ferrous hemes. Both channels could effectively quench NO bioactivity. More recent wo...

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Main Authors: Luchsinger, Benjamin P., Rich, Eric N., Gow, Andrew J., Williams, Elizabeth M., Stamler, Jonathan S., Singel, David J.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC141017/
https://ncbi.nlm.nih.gov/pubmed/12524454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0233287100
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