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Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA
Autosomal dominant dyskeratosis congenita (DKC), as well as aplastic anemia, has been linked to mutations in the RNA component of telomerase, the ribonucleoprotein responsible for telomere maintenance. Here we examine the effect of the DKC mutations on the structure and stability of human telomerase...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC141015/ https://ncbi.nlm.nih.gov/pubmed/12525685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242720799 |
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