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Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA

Autosomal dominant dyskeratosis congenita (DKC), as well as aplastic anemia, has been linked to mutations in the RNA component of telomerase, the ribonucleoprotein responsible for telomere maintenance. Here we examine the effect of the DKC mutations on the structure and stability of human telomerase...

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Bibliografski detalji
Glavni autori: Theimer, Carla A., Finger, L. David, Trantirek, Lukas, Feigon, Juli
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC141015/
https://ncbi.nlm.nih.gov/pubmed/12525685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242720799
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