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Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources

BACKGROUND: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons and EST and protein alignments. However, such evidence is often incomplete and usually uncertain. The extrinsic evidence is...

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Bibliografiske detaljer
Main Authors: Stanke, Mario, Schöffmann, Oliver, Morgenstern, Burkhard, Waack, Stephan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409804/
https://ncbi.nlm.nih.gov/pubmed/16469098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-62
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