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Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs

RNA interference is a cellular process of gene silencing in which small duplexes of RNA specifically target a homologous sequence for cleavage by cellular ribonucleases. The introduction of ≈22-nt small interfering RNAs (siRNAs) into mammalian cells can specifically silence cellular mRNAs without in...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Randall, Glenn, Grakoui, Arash, Rice, Charles M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140937/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12518066/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0235524100
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