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Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs

RNA interference is a cellular process of gene silencing in which small duplexes of RNA specifically target a homologous sequence for cleavage by cellular ribonucleases. The introduction of ≈22-nt small interfering RNAs (siRNAs) into mammalian cells can specifically silence cellular mRNAs without in...

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Autors principals: Randall, Glenn, Grakoui, Arash, Rice, Charles M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC140937/
https://ncbi.nlm.nih.gov/pubmed/12518066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0235524100
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