Alphavirus Minus-Strand Synthesis and Persistence in Mouse Embryo Fibroblasts Derived from Mice Lacking RNase L and Protein Kinase R

We report our studies to probe the possible role of the host response to double-stranded RNA in cessation of alphavirus minus-strand synthesis. Mouse embryo fibroblasts (MEF) from Mx1-deficient mice that also lack either the protein kinase R (PKR) or the latent RNase L or both PKR and RNase L were s...

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Pubblicato in:	J Virol
Autori principali:	Sawicki, Dorothea L., Silverman, Robert H., Williams, Bryan R., Sawicki, Stanley G.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Virus-Cell Interactions
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140908/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12525614/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.3.1801-1811.2003
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