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Functional Analysis of nsP3 Phosphoprotein Mutants of Sindbis Virus

Alphavirus nsP3 phosphoprotein is essential for virus replication and functions initially within polyprotein P123 or P23 components of the short-lived minus-strand replicase, and upon polyprotein cleavage, mature nsP3 likely functions also in plus-strand synthesis. We report the identification of a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dé, Indra, Fata-Hartley, Cori, Sawicki, Stanley G., Sawicki, Dorothea L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC296081/
https://ncbi.nlm.nih.gov/pubmed/14645567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13106-13116.2003
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