Enhancement of Antibodies to the Human Immunodeficiency Virus Type 1 Envelope by Using the Molecular Adjuvant C3d

DNA vaccines expressing the envelope (Env) protein of the human immunodeficiency virus have been relatively ineffective at generating high-titer, long-lasting, neutralizing antibodies in a variety of animal models. In this study, the murine and human homologues of the complement component, C3d, were...

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Bibliographische Detailangaben
Hauptverfasser: Green, Thomas D., Montefiori, David C., Ross, Ted M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC140896/
https://ncbi.nlm.nih.gov/pubmed/12525639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.3.2046-2055.2003
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