Novel Viral Disease Control Strategy: Adenovirus Expressing Alpha Interferon Rapidly Protects Swine from Foot-and-Mouth Disease

We have previously shown that replication of foot-and-mouth disease virus (FMDV) is highly sensitive to alpha/beta interferon (IFN-α/β). In the present study, we constructed recombinant, replication-defective human adenovirus type 5 vectors containing either porcine IFN-α or IFN-β (Ad5-pIFNα or Ad5-...

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Bibliografske podrobnosti

izdano v:	J Virol
Principais autores:	Chinsangaram, Jarasvech, Moraes, Mauro P., Koster, Marla, Grubman, Marvin J.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2003
Teme:	Vaccines and Antiviral Agents
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140819/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12502879/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.2.1621-1625.2003
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