Novel Viral Disease Control Strategy: Adenovirus Expressing Alpha Interferon Rapidly Protects Swine from Foot-and-Mouth Disease

We have previously shown that replication of foot-and-mouth disease virus (FMDV) is highly sensitive to alpha/beta interferon (IFN-α/β). In the present study, we constructed recombinant, replication-defective human adenovirus type 5 vectors containing either porcine IFN-α or IFN-β (Ad5-pIFNα or Ad5-...

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Detalhes bibliográficos
Main Authors: Chinsangaram, Jarasvech, Moraes, Mauro P., Koster, Marla, Grubman, Marvin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140819/
https://ncbi.nlm.nih.gov/pubmed/12502879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.1621-1625.2003
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