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Elucidation of tRNA-dependent editing by a class II tRNA synthetase and significance for cell viability

Editing of misactivated amino acids by class I tRNA synthetases is encoded by a specialized internal domain specific to class I enzymes. In contrast, little is known about editing activities of the structurally distinct class II enzymes. Here we show that the class II alanyl-tRNA synthetase (AlaRS)...

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Udgivet i:EMBO J
Principais autores: Beebe, Kirk, Ribas de Pouplana, Lluis, Schimmel, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2003
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140749/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12554667/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg065
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