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Blocking site-to-site translocation of a misactivated amino acid by mutation of a class I tRNA synthetase

The genetic code is established by the aminoacylation reactions of tRNA synthetases. Its accuracy depends on editing reactions that prevent amino acids from being assigned to incorrect codons. A group of class I synthetases share a common insertion that encodes a distinct site for editing that is ab...

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Detalhes bibliográficos
Main Authors: Bishop, Anthony C., Nomanbhoy, Tyzoon K., Schimmel, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC117349/
https://ncbi.nlm.nih.gov/pubmed/11782529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012611299
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