A conserved tyrosine in the neck of a fungal kinesin regulates the catalytic motor core
The neck domain of fungal conventional kinesins displays characteristic properties which are reflected in a specific sequence pattern. The exchange of the strictly conserved Tyr 362, not present in animals, into Lys, Cys or Phe leads to a failure to dimerize. The destabilizing effect is confirmed by...
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| 出版年: | EMBO J |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12554646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg036 |
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