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A conserved tyrosine in the neck of a fungal kinesin regulates the catalytic motor core
The neck domain of fungal conventional kinesins displays characteristic properties which are reflected in a specific sequence pattern. The exchange of the strictly conserved Tyr 362, not present in animals, into Lys, Cys or Phe leads to a failure to dimerize. The destabilizing effect is confirmed by...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140721/ https://ncbi.nlm.nih.gov/pubmed/12554646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg036 |
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