Promoter Sequences of Varicella-Zoster Virus Glycoprotein I Targeted by Cellular Transactivating Factors Sp1 and USF Determine Virulence in Skin and T Cells in SCIDhu Mice In Vivo

Varicella-zoster virus (VZV) glycoprotein I is dispensable in cell culture but necessary for infection of human skin and T cells in SCIDhu mice in vivo. The gI promoter contains an activating upstream sequence that binds the cellular transactivators specificity factor 1 (Sp1) and upstream stimulator...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Ito, Hideki, Sommer, Marvin H., Zerboni, Leigh, He, Hongying, Boucaud, Dwayne, Hay, John, Ruyechan, William, Arvin, Ann M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2003
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC140613/
https://ncbi.nlm.nih.gov/pubmed/12477854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.489-498.2003
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki