Promoter Sequences of Varicella-Zoster Virus Glycoprotein I Targeted by Cellular Transactivating Factors Sp1 and USF Determine Virulence in Skin and T Cells in SCIDhu Mice In Vivo

Varicella-zoster virus (VZV) glycoprotein I is dispensable in cell culture but necessary for infection of human skin and T cells in SCIDhu mice in vivo. The gI promoter contains an activating upstream sequence that binds the cellular transactivators specificity factor 1 (Sp1) and upstream stimulator...

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Detalhes bibliográficos
Main Authors: Ito, Hideki, Sommer, Marvin H., Zerboni, Leigh, He, Hongying, Boucaud, Dwayne, Hay, John, Ruyechan, William, Arvin, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2003
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140613/
https://ncbi.nlm.nih.gov/pubmed/12477854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.489-498.2003
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